adjuvant regional nodal irradiation recommendations after acosog z0011 (alliance) trial results: “our doubts and uncertainties maybe traitors for undertreated patients”
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منابع مشابه
Evolution of axillary nodal staging in breast cancer: clinical implications of the ACOSOG Z0011 trial.
BACKGROUND Management of the axilla in breast cancer patients has evolved from routine axillary lymph node dissection (ALND) for all patients to a highly selective approach based on the assessment of the sentinel lymph nodes (SLNs) as well as tumor and patient characteristics. Although ALND continues to have an important role in staging and regional control for many breast cancer patients, rece...
متن کاملThe feasibility of the ACOSOG Z0011 Criteria to Chinese Breast Cancer Patients: A Multicenter Study
The aim of this study was to determine the feasibility of the Z0011 criteria to Chinese breast cancer patients. An survey about the Z0011 trial was distributed and we collected 658 consecutive patients with axillary lymph node dissection (ALND) after positive sentinel lymph node (SLN) biopsy from five centers' databases and grouped them as eligible or ineligible for omitting ALND according to t...
متن کاملFactors associated with local-regional recurrence after a negative sentinel node dissection: results of the ACOSOG Z0010 trial.
OBJECTIVE To determine factors important in local-regional recurrence (LRR) in patients with negative sentinel lymph nodes (SLNs) by hematoxylin and eosin (H&E) staining. BACKGROUND Z0010 was a prospective multicenter trial initiated in 1999 by the American College of Surgeons Oncology Group to evaluate occult disease in SLNs and bone marrow of early-stage breast cancer patients. Participants...
متن کاملOutcomes of Sentinel Lymph Node Dissection Alone vs. Axillary Lymph Node Dissection in Early Stage Invasive Lobular Carcinoma: A Retrospective Study of the Surveillance, Epidemiology and End Results (SEER) Database
BACKGROUND The American College of Surgeons Oncology Group (ACOSOG) Z0011 trial demonstrated no difference in local-regional recurrence (LRR), disease-specific survival (DSS) or overall survival (OS) for sentinel lymph node dissection (SLND) and completion axillary lymph node dissection (ALND) among patients undergoing breast-conserving therapy for clinical T1-T2, N0 breast cancer with 1 or 2 p...
متن کاملPoint–Counterpoint Review Point It Is Not Always Necessary to Do Axillary Dissection for T1 and T2 Breast Cancer
Axillary lymph node dissection (ALND) has been a part of breast cancer management since the 1900s. The idea that axillary metastases do not require surgical removal is a repudiation of the Halstedian concept of breast cancer biology, yet multiple prospective randomized studies show that the incidence of nodal recurrence in patients not having ALND is substantially lower than expected, based on ...
متن کاملIt Is Not Always Necessary to Do Axillary Dissection for T1 and T2 Breast Cancer
Axillary lymph node dissection (ALND) has been a part of breast cancer management since the 1900s. The idea that axillary metastases do not require surgical removal is a repudiation of the Halstedian concept of breast cancer biology, yet multiple prospective randomized studies show that the incidence of nodal recurrence in patients not having ALND is substantially lower than expected, based on ...
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عنوان ژورنال:
archives of breast cancerجلد ۲، شماره ۱، صفحات ۱-۲
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